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[WORKSHOP] ANDREW 3 - (Ultra) Early intervention in NDD: Understanding development to facilitate functioning

synthesized in planta from tryptamine. In this experiment a potential novel dimeric MIA was discovered in leaf still unknown in which tissues Rauvolfia produce reserpine and where the individual steps in the biosynthetic DESI-MSI. In stem tissue reserpine and many of the intermediates were found compartmentalized in the xylem proposed intermediates were detected in the normal version as well as in the isotope labelled versions confirming comprehensive spatial mapping of metabolites in the R. tetraphylla plant. In addition the article also contains In this study published in Phytochemistry, we explore how matrix assisted laser desorption ionization (DESI) mass spectrometry imaging (MSI) can be used in the investigation of a proposed biosynthetic pathway Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry

insights into the regulation of specialized metabolism in plants. Nat Plants. 2022 . doi 10.1038 s41477-022-01288-7 network. Specialized metabolites have important roles in development and adaptation to external cues and they We also discuss how this new knowledge could help in improving strategies to produce useful plant-derived Published in Nature Plants, this review focuses on translational, transcriptional, epigenetic and chromatin-based and also discuss how this new knowledge could help in improving strategies to produce useful plant-derived insights into the regulation of specialized metabolism in plants

Courdavault V. Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization relying on the efficient recycling of enzyme co-factors in yeast to fulfill the synthesis of caffeic acid (CaA) high titer production of valuable natural products in yeast. Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization

anticancer monoterpene indole alkaloids in Catharanthus roseus. RNA in situ hybridization has proven a key Pioneer work in 1999 discovered the involvement of epidermis and laticifer idioblasts in the intermediate involved in this pathway. We introduce here a comparison of advantages and drawbacks of in situ hybridization RNA In Situ Hybridization of Paraffin Sections to Characterize the Multicellular Compartmentation of block organization of the pathway. Since then RNA in situ hybridization was routinely used to map the In this Chapter of the "Catharanthus roseus, Methods and Protocols" book, we provide a step-by-step protocol plant tissue array preparation, prehybridization, in situ hybridization, stringent washing and immunodetection RNA In Situ Hybridization of Paraffin Sections to Characterize the Multicellular Compartmentation of

Identifying Major Drivers of Antioxidant Activities in Complex Polyphenol Mixtures from Grape Canes. Molecules considering possible interactions that may occur in complex polyphenol mixture. Using UPLC-MS-based metabolomics classification we explored the polyphenol variations in grape cane extracts from a collection of European In this article published in Molecules, we identified the main drivers of antioxidant activities in polyphenol-rich polyphenol-rich grape cane extracts in European varieties. Congrats to our PhD student Manon Ferrier Identifying Major Drivers of Antioxidant Activities in Complex Polyphenol Mixtures from Grape Canes

minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis . G3 Bethesda These genes were functionally annotated and used in a comparative genomic analysis to establish gene minor genome finally assembled! Our new publication in G3! The Vinca minor plant synthesizes monoterpene minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis

"Picturing Empires: Photography and social change in 19th century multi-ethnic Environnments" "The beginning of industrial photography in France : Which representations of the working environment

life in France during the Renaissance period What music for example was heard on the streets or in the towns and cities in the construction of their civic identity What role did music play in the popular politics use of music in civic festivals among them processions and ceremonial entries and ways in which surviving University of Cambridge - UK IN RESIDENCE AT Centre for Advanced Studies in the Renaissance CESR CNRS University Presentation France s remarkable place in the history of music during the Renaissance period is undeniable Studium Conferences] Musical life and civic identity in Renaissance France (c.1500-c.1650)

consumption in the performing arts whether for the celebration of civic and court festivals or in the contexts economic issues which are generally left in the background. In an attempt to fill this lacuna this conference Italian Renaissance Studies - IT IN RESIDENCE AT Centre for Advanced Studies in the Renaissance CESR CNRS University the social cultural and economic capital invested in and gained by ephemeral consumption. Alongside theatre this conference brings together scholars working in the fields of art history and architecture literature Economics of Spectacle. Funding the Ephemeral Arts in Early Modern Europe